T cells suppress memory-dependent rapid mucous cell metaplasia in mouse airways

T cells suppress memory-dependent rapid mucous cell metaplasia in mouse airways

Abstract Background Airway epithelial cells (AECs) are crucial for mucosal and adaptive immunity but whether these cells respond in a memory-dependent manner is poorly studied. Previously, we have reported that LPS intratracheal instillation in rodents causes extensive neutrophilic inflammation and...

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Bibliographic Details
Main Authors: Hitendra S. Chand, Yohannes A. Mebratu, Marena Montera, Yohannes Tesfaigzi
Format: Article
Language:English
Published: BMC 2016-10-01
Series:Respiratory Research
Subjects:
Mucous cell metaplasia
Epithelial memory
LPS
T cells
Toll-like receptor 4
Epidermal growth factor receptor
Online Access:http://link.springer.com/article/10.1186/s12931-016-0446-0

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http://link.springer.com/article/10.1186/s12931-016-0446-0

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