Pou4f1 and pou4f2 are dispensable for the long-term survival of adult retinal ganglion cells in mice.
To investigate the role of Pou4f1 and Pou4f2 in the survival of adult retinal ganglion cells (RGCs).Conditional alleles of Pou4f1 and Pou4f2 were generated (Pou4f1loxP and Pou4f2loxP respectively) for the removal of Pou4f1 and Pou4f2 in adult retinas. A tamoxifen-inducible Cre was used to delete Pou...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2014-01-01
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| Series: | PLoS ONE |
| Online Access: | http://europepmc.org/articles/PMC3988073?pdf=render |