Increased Expression and Redistribution of the Antiapoptotic Molecule Bcl-xL in Parkinson's Disease

Increased Expression and Redistribution of the Antiapoptotic Molecule Bcl-xL in Parkinson's Disease

In the present study, we tried to clarify the potentially protective role of Bcl-xL, an anti-apoptotic member of the Bcl-2 family of proteins, in Parkinson's disease (PD). Using in situ hybridization on human postmortem mesencephalon sections, we show that in PD patients Bcl-xL mRNA expression...

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Bibliographic Details
Main Authors: Andreas Hartmann, Annick Mouatt-Prigent, Miquel Vila, Nacer Abbas, Céline Perier, Baptiste A. Faucheux, Sheela Vyas, Etienne C. Hirsch
Format: Article
Language:English
Published: Elsevier 2002-06-01
Series:Neurobiology of Disease
Subjects:
Parkinson's disease
apoptosis
mitochondria
Bcl-xL
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996102904948

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http://www.sciencedirect.com/science/article/pii/S0969996102904948

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