Suppressive effect of mesenchymal stromal cells on interferon-γ-producing capability of spleen cells was specifically enhanced through humoral mediator(s) from mouse oral squamous cell carcinoma Sq-1979 Cells In Vitro

Suppressive effect of mesenchymal stromal cells on interferon-γ-producing capability of spleen cells was specifically enhanced through humoral mediator(s) from mouse oral squamous cell carcinoma Sq-1979 Cells In Vitro

Aim: The aim of this study was to compare the immunomodulatory effects in the tumor milieu of mouse oral squamous cell carcinoma (OSCC) cells harboring primary and advanced phenotypes. We established an in vitro co-culture system using mouse OSCC cells, spleen cells, and mesenchymal stromal cells. M...

Full description

Bibliographic Details
Main Authors: Toshihiro Inagaki, Masako Mizuno-Kamiya, Eiji Takayama, Harumi Kawaki, Eiichi Chihara, Yasunori Muramatsu, Shinichiro Sumitomo, Nobuo Kondoh
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2018-01-01
Series:Cancer Translational Medicine
Subjects:
Immune suppression
interferon-γ
OSCC
reciprocal interaction
spleen cells
stromal cells
Online Access:http://www.cancertm.com/article.asp?issn=2395-3977;year=2018;volume=4;issue=1;spage=9;epage=16;aulast=Inagaki

Internet

http://www.cancertm.com/article.asp?issn=2395-3977;year=2018;volume=4;issue=1;spage=9;epage=16;aulast=Inagaki

Similar Items