Inflammatory Mediators in Glioma Microenvironment Play a Dual Role in Gliomagenesis and Mesenchymal Stem Cell Homing: Implication for Cellular Therapy

Inflammatory Mediators in Glioma Microenvironment Play a Dual Role in Gliomagenesis and Mesenchymal Stem Cell Homing: Implication for Cellular Therapy

Glioblastoma is the most aggressive malignant primary brain tumor, with a dismal prognosis and a devastating overall survival. Despite aggressive surgical resection and adjuvant treatment, average survival remains approximately 14.6 months. The brain tumor microenvironment is heterogeneous, comprisi...

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Bibliographic Details
Main Authors: Rawan Al-kharboosh, Karim ReFaey, MD, Montserrat Lara-Velazquez, MD, Sanjeet S. Grewal, MD, Jaime Imitola, MD, Alfredo Quiñones-Hinojosa, MD
Format: Article
Language:English
Published: Elsevier 2020-08-01
Series:Mayo Clinic Proceedings: Innovations, Quality & Outcomes
Online Access:http://www.sciencedirect.com/science/article/pii/S2542454820300710

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http://www.sciencedirect.com/science/article/pii/S2542454820300710

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