Generation of familial amyloidotic polyneuropathy-specific induced pluripotent stem cells

Generation of familial amyloidotic polyneuropathy-specific induced pluripotent stem cells

Familial amyloidotic polyneuropathy (FAP) is a hereditary amyloidosis induced by amyloidogenic transthyretin (ATTR). Because most transthyretin (TTR) in serum is synthesized by the liver, liver transplantation (LT) is today the only treatment available to halt the progression of FAP, even though LT...

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Main Authors: Kaori Isono, Hirofumi Jono, Yuki Ohya, Nobuaki Shiraki, Taiji Yamazoe, Ayaka Sugasaki, Takumi Era, Noemi Fusaki, Masayoshi Tasaki, Mitsuharu Ueda, Satoru Shinriki, Yukihiro Inomata, Shoen Kume, Yukio Ando
Format: Article
Language:English
Published: Elsevier 2014-03-01
Series:Stem Cell Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1873506114000075

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http://www.sciencedirect.com/science/article/pii/S1873506114000075

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