Computational estimates of mechanical constraints on cell migration through the extracellular matrix.

Cell migration through a three-dimensional (3D) extracellular matrix (ECM) underlies important physiological phenomena and is based on a variety of mechanical strategies depending on the cell type and the properties of the ECM. By using computer simulations of the cell's mid-plane, we investiga...

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Bibliographic Details
Main Authors: Ondrej Maxian, Alex Mogilner, Wanda Strychalski
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-08-01
Series:PLoS Computational Biology
Online Access:https://doi.org/10.1371/journal.pcbi.1008160