The Cre–loxP System: A Versatile Tool for Targeting Genes in a Cell- and Stage-Specific Manner
Gene-targeted mice, derived from embryonic stem cells, are useful tools to study gene function during development. However, if the inactivation of the target gene results in embryonic lethality, the postdevelopmental function of the gene cannot be further studied. The Cre recombinase-loxP (Cre–loxP)...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
SAGE Publishing
2000-11-01
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| Series: | Cell Transplantation |
| Online Access: | https://doi.org/10.1177/096368970000900607 |