A bioactive polysaccharide TLH-3 isolated from Tricholoma lobayense protects against oxidative stress-induced premature senescence in cells and mice

A bioactive polysaccharide TLH-3 isolated from Tricholoma lobayense protects against oxidative stress-induced premature senescence in cells and mice

To inform rational therapeutics to alleviate many senescence-related diseases in terms of the pathogenic pathways, we investigated the protective mechanisms of TLH-3 against premature senescence in tert-butyl hydroperoxide (t-BHP)-induced human embryonic lung fibroblast (HELF) cells model and d-gala...

Full description

Bibliographic Details
Main Authors: Wen-Juan Pan, Qiu-Ying Ding, Ya Wang, Dan-Dan Wang, Yong-Ming Lu, Wei-Wei Yang, Zheng-Nan Cai, Xiao-Du Cheng, Wen-Na Zhang, Yan Chen
Format: Article
Language:English
Published: Elsevier 2018-03-01
Series:Journal of Functional Foods
Subjects:
Alleviate
Bioactive polysaccharide TLH-3
Oxidative stress-induced premature senescence
P53
Senescence-associated β-galactosidase
Online Access:http://www.sciencedirect.com/science/article/pii/S1756464617308046

Internet

http://www.sciencedirect.com/science/article/pii/S1756464617308046

Similar Items