Mouse closed head traumatic brain injury replicates the histological tau pathology pattern of human disease: characterization of a novel model and systematic review of the literature

Mouse closed head traumatic brain injury replicates the histological tau pathology pattern of human disease: characterization of a novel model and systematic review of the literature

Abstract Traumatic brain injury (TBI) constitutes one of the strongest environmental risk factors for several progressive neurodegenerative disorders of cognitive impairment and dementia that are characterized by the pathological accumulation of hyperphosphorylated tau (p-Tau). It has been questione...

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Bibliographic Details
Main Authors: Aydan Kahriman, James Bouley, Thomas W. Smith, Daryl A. Bosco, Amanda L. Woerman, Nils Henninger
Format: Article
Language:English
Published: BMC 2021-06-01
Series:Acta Neuropathologica Communications
Subjects:
Animal model
Chronic traumatic encephalopathy
Concussion
Systematic review
Tauopathy
Traumatic brain injury
Online Access:https://doi.org/10.1186/s40478-021-01220-8

Internet

https://doi.org/10.1186/s40478-021-01220-8

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