Lentiviral vector mediated thymidine kinase expression in pluripotent stem cells enables removal of tumorigenic cells.
Embryonic stem cells (ES) and induced pluripotent stem (iPS) cells represent promising tools for cell-based therapies and regenerative medicine. Nevertheless, implantation of ES cell derived differentiated cells holds the risk of teratoma formation due to residual undifferentiated cells. In order to...
Main Authors: | Tiong-Ti Lim, Caroline Geisen, Michael Hesse, Bernd K Fleischmann, Katrin Zimmermann, Alexander Pfeifer |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2013-01-01
|
Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC3728319?pdf=render |
Similar Items
-
Potent and reversible lentiviral vector restriction in murine induced pluripotent stem cells
by: Franziska K. Geis, et al.
Published: (2017-05-01) -
Correction to: Potent and reversible lentiviral vector restriction in murine induced pluripotent stem cells
by: Franziska K. Geis, et al.
Published: (2017-10-01) -
Increased Cytotoxicity of Herpes Simplex Virus Thymidine Kinase Expression in Human Induced Pluripotent Stem Cells
by: Chizuru Iwasawa, et al.
Published: (2019-02-01) -
Degradation of Human Thymidine Kinase During Cell Cycle
by: TSAI, I-CHUN, et al.
Published: (2000) -
Cell cycle-associated thymidine kinase regulation in friend erythroleukaemia cells
by: Thompson, Christopher C. M.
Published: (1993)