Synthesis of 16 New Hybrids from Tetrahydropyrans Derivatives and Morita˗Baylis˗Hillman Adducts: In Vitro Screening against Leishmania donovani

Synthesis of 16 New Hybrids from Tetrahydropyrans Derivatives and Morita˗Baylis˗Hillman Adducts: In Vitro Screening against Leishmania donovani

Leishmaniases are a group of neglected tropical diseases (NTDs) caused by protozoan parasites from >20 Leishmania species. Visceral leishmaniasis (VL), also known as kala‐aza, is the most severe form of leishmaniasis, usually fatal in the absence of treatment in 95% of cases. The Morita‐Bayli...

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Bibliographic Details
Main Authors: Suervy Canuto de Oliveira Sousa, Juliana da Câmara Rocha, Tatjana de Souza Lima Keesen, Everton da Paz Silva, Priscilla Anne Castro de Assis, João Paulo Gomes de Oliveira, Saulo Luís Capim, Francisco José Seixas Xavier, Bruno Guimarães Marinho, Fábio Pedrosa Lins Silva, Claudio Gabriel Lima‐Junior, Mário Luiz Araújo de Almeida Vasconcellos
Format: Article
Language:English
Published: MDPI AG 2017-01-01
Series:Molecules
Subjects:
Antileishmanial Morita‐Baylis‐Hillman adducts
 opioids tetrahydropyrans derivatives
  molecular hybridization
 Leishmania donovani.
Online Access:http://www.mdpi.com/1420-3049/22/2/207

Internet

http://www.mdpi.com/1420-3049/22/2/207

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