Screening the genome for HCC-specific CpG methylation signatures as biomarkers for diagnosis and prognosis evaluation

Abstract Background Hepatocellular carcinoma (HCC) is one of the most common and invasive malignant tumors in the world. The change in DNA methylation is a key event in HCC. Methods Methylation datasets for HCC and 17 other types of cancer were downloaded from The Cancer Genome Atlas (TCGA). The CpG...

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Bibliographic Details
Main Authors: Rui-kun Zhang, Jia-lin Liu
Format: Article
Language:English
Published: BMC 2021-06-01
Series:BMC Medical Genomics
Online Access:https://doi.org/10.1186/s12920-021-01015-9