Watch Out for a Second SNP: Focus on Multi-Nucleotide Variants in Coding Regions and Rescued Stop-Gained

Watch Out for a Second SNP: Focus on Multi-Nucleotide Variants in Coding Regions and Rescued Stop-Gained

Most single-nucleotide polymorphisms (SNPs) are located in non-coding regions, but the fraction usually studied is harbored in protein-coding regions because potential impacts on proteins are relatively easy to predict by popular tools such as the Variant Effect Predictor. These tools annotate varia...

Full description

Bibliographic Details
Main Authors:	Fabien Degalez, Frédéric Jehl, Kévin Muret, Maria Bernard, Frédéric Lecerf, Laetitia Lagoutte, Colette Désert, Frédérique Pitel, Christophe Klopp, Sandrine Lagarrigue
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2021-07-01
Series:	Frontiers in Genetics
Subjects:	MNV SNP variation rescued stop-gained SLC27A4 FATP4
Online Access:	https://www.frontiersin.org/articles/10.3389/fgene.2021.659287/full

Similar Items

Does TBC1D4 (AS160) or TBC1D1 Deficiency Affect the Expression of Fatty Acid Handling Proteins in the Adipocytes Differentiated from Human Adipose-Derived Mesenchymal Stem Cells (ADMSCs) Obtained from Subcutaneous and Visceral Fat Depots?
by: Agnieszka Mikłosz, et al.
Published: (2021-06-01)

Intestinal Saturated Long-Chain Fatty Acid, Glucose and Fructose Transporters and Their Inhibition by Natural Plant Extracts in Caco-2 Cells
by: Katharina Schreck, et al.
Published: (2018-10-01)

تأثیر تمرین تناوبی شدید بر بیان ژن CTRP15 عضلانی و انتقال‌دهنده‌های اسید چرب آدیپوسیت‌ها در موش‌های صحرایی نژاد ویستار
by: حامد برزگر, et al.
Published: (2018-04-01)

Solute Carrier Family 27 Member 4 (SLC27A4) Enhances Cell Growth, Migration, and Invasion in Breast Cancer Cells
by: Meng-Chi Yen, et al.
Published: (2018-11-01)

RNA-Seq Data for Reliable SNP Detection and Genotype Calling: Interest for Coding Variant Characterization and Cis-Regulation Analysis by Allele-Specific Expression in Livestock Species
by: Frédéric Jehl, et al.
Published: (2021-06-01)

Analyse du phénotype visuel d'un modèle de souris déficiente pour la protéine FATP1
by: Chekroud, Karim
Published: (2010)

Enterotoxigenic Escherichia coli Interferes FATP4-Dependent Long-Chain Fatty Acid Uptake of Intestinal Epithelial Enterocytes via Phosphorylation of ERK1/2-PPARγ Pathway
by: Zhi Li, et al.
Published: (2019-06-01)

The Oxysterol 25-Hydroxycholesterol Inhibits Replication of Murine Norovirus
by: Ghada T. Shawli, et al.
Published: (2019-01-01)

Survivin Overexpression Has a Negative Effect on Feline Calicivirus Infection
by: Oscar Salvador Barrera-Vázquez, et al.
Published: (2019-10-01)

Genistein Induces Increase in Fluid pH, Na+ and HCO3− Concentration, SLC26A6 and SLC4A4 (NBCe1)-B Expression in the Uteri of Ovariectomized Rats
by: Asma Chinigarzadeh, et al.
Published: (2014-01-01)

Protein-mediated palmitate uptake and expression of fatty acid transport proteins in heart giant vesicles
by: Joost J.F.P. Luiken, et al.
Published: (1999-06-01)

Antiviral Potential of Plants against Noroviruses
by: Jolanta Sarowska, et al.
Published: (2021-08-01)

Fatigue Strength Analysis of S34MnV Steel by Accelerated Staircase Test
by: Ekaputra I. M. W., et al.
Published: (2020-05-01)

Ontogenic Expression Pattern and Genetic Polymorphisms of the Fatty Acid Transport Protein 4 (<em>FATP4</em>) Gene in Chinese Chicken Populations
by: Yi-Ping Liu, et al.
Published: (2012-06-01)

Effect of Feeding Conditions on the Methylation Status of Fatp1 Gene in Chicken Breast Muscle
by: G Gao, et al.

Simple and facilitated diffusion of long chain fatty acids in the pathogenesis of nonalcoholic fatty liver disease
by: Klaudia Berk, et al.
Published: (2017-12-01)

Fatigue lifetime of 20MnV6 steel with holes manufactured by various methods
by: Otakar Bokůvka, et al.
Published: (2018-07-01)

Cell Cycle Arrest is a Conserved Function of Norovirus VPg Proteins
by: Alice McSweeney, et al.
Published: (2019-03-01)

Composition of the Intestinal Microbiota Determines the Outcome of Virus-Triggered Colitis in Mice
by: Silvia Bolsega, et al.
Published: (2019-07-01)

The N-terminal cytoplasmic region of NCBE displays features of an intrinsic disordered structure and represents a novel target for specific drug screening
by: Kaare eBjerregaard-Andersen, et al.
Published: (2013-11-01)

Expression Analysis of Zinc Transporters in Nervous Tissue Cells Reveals Neuronal and Synaptic Localization of ZIP4
by: Chiara A. De Benedictis, et al.
Published: (2021-04-01)

THE REGULATION OF FATTY ACID TRANSPORT AND TRANSPORTERS IN INSULIN-, AND CONTRACTION-STIMULATED SKELETAL MUSCLE
by: Jain, Swati
Published: (2011)

Disturbed acid-base transport: an emerging cause of hypertension
by: Ebbe eBoedtkjer, et al.
Published: (2013-12-01)

An integrative atlas of chicken long non-coding genes and their annotations across 25 tissues
by: Frédéric Jehl, et al.
Published: (2020-11-01)

Author Correction: An integrative atlas of chicken long non-coding genes and their annotations across 25 tissues
by: Frédéric Jehl, et al.
Published: (2021-04-01)

Natural infection of murine norovirus in conventional and specific pathogen-free (SPF) laboratory mice
by: Takeo eOhsugi, et al.
Published: (2013-01-01)

Efeito da albumina modificada por glicação avançada sobre a expressão do gene SLC2A4 em músculo esquelético.
by: Pinto Júnior, Danilo Antônio Corrêa
Published: (2016)

Serotonin Transporter Gene (SLC6A4) Polymorphism and Mucosal Serotonin Levels in Southeastern Iranian Patients with Irritable Bowel Syndrome
by: Mojgan Mohammadi, et al.
Published: (2017-01-01)

Residual feed intake phenotype and gender affect the expression of key genes of the lipogenesis pathway in subcutaneous adipose tissue of beef cattle
by: Clare McKenna, et al.
Published: (2018-09-01)

Placental SLC38A4 gene polymorphisms 1304 G > A and 292 C > T, and their association with glucose > 95 mg/dl in normal weight full-term healthy newborns
by: Carlos Galaviz-Hernández, et al.
Published: (2021-07-01)

Correlation Analysis of Relative Expression of Apob, Adfp and Fatp1 with Lipid Metabolism in Daweishan Mini Chickens
by: X Decai, et al.

Poultry fat decreased fatty acid transporter protein mRNA expression and affected fatty acid composition in chickens
by: Yuan Jianmin, et al.
Published: (2012-05-01)

Long noncoding RNAs in lipid metabolism: literature review and conservation analysis across species
by: Kevin Muret, et al.
Published: (2019-11-01)

Contribution of SLC26A4 to the molecular diagnosis of nonsyndromic prelingual sensorineural hearing loss in a Brazilian cohort
by: Simone da Costa e Silva Carvalho, et al.
Published: (2018-08-01)

The Human Pendrin Promoter Contains two N4 GAS Motifs with Different Functional Relevance
by: Simone Vanoni, et al.
Published: (2013-12-01)

Antiviral Effects of <i>Lindera</i> <i>obtusiloba</i> Leaf Extract on Murine Norovirus-1 (MNV-1), a Human Norovirus Surrogate, and Potential Application to Model Foods
by: Diana Solis-Sanchez, et al.
Published: (2020-10-01)

TGFβ Signaling Increases Net Acid Extrusion, Proliferation and Invasion in Panc-1 Pancreatic Cancer Cells: SMAD4 Dependence and Link to Merlin/NF2 Signaling
by: Raj R. Malinda, et al.
Published: (2020-05-01)

Genome-wide transcriptomic analysis of the forebrain of postnatal Slc13a4 +/− mice
by: Tracey J. Harvey, et al.
Published: (2021-07-01)

Approche intégrative des facteurs biologiques et psychologiques associés au pronostic des troubles de l'humeur
by: Consoloni, Julia-Lou
Published: (2017)

The Implication of PGC-1α on Fatty Acid Transport across Plasma and Mitochondrial Membranes in the Insulin Sensitive Tissues
by: Elżbieta Supruniuk, et al.
Published: (2017-11-01)

Cannot write session to /tmp/vufind_sessions/sess_o39jadsto1cl3b2e0acmsv89f5