CEACAM6 promotes gastric cancer invasion and metastasis by inducing epithelial-mesenchymal transition via PI3K/AKT signaling pathway.

CEACAM6 promotes gastric cancer invasion and metastasis by inducing epithelial-mesenchymal transition via PI3K/AKT signaling pathway.

Overexpressed CEACAM6 in tumor tissues plays important roles in invasion, metastasis and anoikis resistance in a variety of human cancers. We recently reported that CEACAM6 expression is upregulated in Gastric cancer (GC) tissues and promoted GC metastasis. Here, we report that CEACAM6 promotes peri...

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Bibliographic Details
Main Authors: Mingde Zang, Baogui Zhang, Yunqiang Zhang, Jianfang Li, Liping Su, Zhenggang Zhu, Qinlong Gu, Bingya Liu, Min Yan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4232574?pdf=render

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http://europepmc.org/articles/PMC4232574?pdf=render

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