Annexin A1 as Neuroprotective Determinant for Blood-Brain Barrier Integrity in Neonatal Hypoxic-Ischemic Encephalopathy

Annexin A1 as Neuroprotective Determinant for Blood-Brain Barrier Integrity in Neonatal Hypoxic-Ischemic Encephalopathy

Blood-brain barrier (BBB) disruption is associated with hypoxia-ischemia (HI) induced brain injury and life-long neurological pathologies. Treatment options are limited. Recently, we found that mesenchymal stem/stromal cell derived extracellular vesicles (MSC-EVs) protected the brain in ovine fetuse...

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Bibliographic Details
Main Authors: Ruth Gussenhoven, Luise Klein, Daan R. M. G. Ophelders, Denise H. J. Habets, Bernd Giebel, Boris W. Kramer, Leon J. Schurgers, Chris P. M. Reutelingsperger, Tim G. A. M. Wolfs
Format: Article
Language:English
Published: MDPI AG 2019-01-01
Series:Journal of Clinical Medicine
Subjects:
Annexin A1/Formyl peptide receptor axis
blood-brain barrier
mesenchymal stem cell-derived extracellular vesicles
neonatal hypoxia-ischemia
therapy
Online Access:https://www.mdpi.com/2077-0383/8/2/137

Internet

https://www.mdpi.com/2077-0383/8/2/137

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