A bioengineering method for modeling alveolar Rhabdomyosarcoma and assessing chemotherapy responses

Rhabdomyosarcoma (RMS) is the most common pediatric soft-tissue malignant tumor. Treatment of RMS usually includes primary tumor resection along with systemic chemotherapy. Two-dimensional (2D) cell culture systems and animal models have been extensively used for investigating the potential efficacy...

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Bibliographic Details
Main Authors: Evan Stefanek, Ehsan Samiei, Mahboubeh Kavoosi, Mohammad Esmaeillou, Kiarash Roustai Geraylow, Arya Emami, Milad Ashrafizadeh, David Perrin, Joseph W Gordon, Mohsen Akbari, Saeid Ghavami
Format: Article
Language:English
Published: Elsevier 2021-01-01
Series:MethodsX
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2215016121002661