Thinking Small: Small Molecules as Potential Synergistic Adjuncts to Checkpoint Inhibition in Melanoma

Thinking Small: Small Molecules as Potential Synergistic Adjuncts to Checkpoint Inhibition in Melanoma

Metastatic melanoma remains the deadliest form of skin cancer. Immune checkpoint inhibition (ICI) immunotherapy has defined a new age in melanoma treatment, but responses remain inconsistent and some patients develop treatment resistance. The myriad of newly developed small molecular (SM) inhibitors...

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Bibliographic Details
Main Authors: Alexander C. Chacon, Alexa D. Melucci, Shuyang S. Qin, Peter A. Prieto
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:International Journal of Molecular Sciences
Subjects:
melanoma
immunotherapy
checkpoint inhibition
small molecules
targeted therapy
precision oncology
Online Access:https://www.mdpi.com/1422-0067/22/6/3228

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https://www.mdpi.com/1422-0067/22/6/3228

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