Linking Ventilator Injury-Induced Leak across the Blood-Gas Barrier to Derangements in Murine Lung Function

Linking Ventilator Injury-Induced Leak across the Blood-Gas Barrier to Derangements in Murine Lung Function

Mechanical ventilation is vital to the management of acute respiratory distress syndrome, but it frequently leads to ventilator-induced lung injury (VILI). Understanding the pathophysiological processes involved in the development of VILI is an essential prerequisite for improving lung-protective ve...

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Bibliographic Details
Main Authors: Bradford J. Smith, Elizabeth Bartolak-Suki, Bela Suki, Gregory S. Roy, Katharine L. Hamlington, Chantel M. Charlebois, Jason H. T. Bates
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-07-01
Series:Frontiers in Physiology
Subjects:
lung injury
mechanical ventilation
ARDS
alveolar leak
surfactant dysfunction
Online Access:http://journal.frontiersin.org/article/10.3389/fphys.2017.00466/full

Internet

http://journal.frontiersin.org/article/10.3389/fphys.2017.00466/full

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