The Pluripotency Factor-Bound Intron 1 of Xist Is Dispensable for X Chromosome Inactivation and Reactivation In Vitro and In Vivo

X chromosome inactivation (XCI) is a dynamically regulated developmental process with inactivation and reactivation accompanying the loss and gain of pluripotency, respectively. A functional relationship between pluripotency and lack of XCI has been suggested, whereby pluripotency transcription fac...

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Bibliographic Details
Main Authors: Alissa Minkovsky, Tahsin Stefan Barakat, Nadia Sellami, Mark Henry Chin, Nilhan Gunhanlar, Joost Gribnau, Kathrin Plath
Format: Article
Language:English
Published: Elsevier 2013-03-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124713000946