GARP is a key molecule for mesenchymal stromal cell responses to TGF‐β and fundamental to control mitochondrial ROS levels

GARP is a key molecule for mesenchymal stromal cell responses to TGF‐β and fundamental to control mitochondrial ROS levels

Abstract Multipotent mesenchymal stromal cells (MSCs) have emerged as a promising cell therapy in regenerative medicine and for autoimmune/inflammatory diseases. However, a main hurdle for MSCs‐based therapies is the loss of their proliferative potential in vitro. Here we report that glycoprotein A...

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Bibliographic Details
Main Authors: Ana Belén Carrillo‐Gálvez, Sheyla Gálvez‐Peisl, Juan Elías González‐Correa, Marina deHaro‐Carrillo, Verónica Ayllón, Pedro Carmona‐Sáez, Verónica Ramos‐Mejía, Pablo Galindo‐Moreno, Francisca E. Cara, Sergio Granados‐Principal, Pilar Muñoz, Francisco Martin, Per Anderson
Format: Article
Language:English
Published: Wiley 2020-05-01
Series:Stem Cells Translational Medicine
Subjects:
DNA damage
mesenchymal stromal cells (MSCs)
proliferation
ROS
TGF‐β
Online Access:https://doi.org/10.1002/sctm.19-0372

Internet

https://doi.org/10.1002/sctm.19-0372

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