ALS blood expression profiling identifies new biomarkers, patient subgroups, and evidence for neutrophilia and hypoxia

ALS blood expression profiling identifies new biomarkers, patient subgroups, and evidence for neutrophilia and hypoxia

Abstract Background Amyotrophic lateral sclerosis (ALS) is a debilitating disease with few treatment options. Progress towards new therapies requires validated disease biomarkers, but there is no consensus on which fluid-based measures are most informative. Methods This study analyzed microarray dat...

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Bibliographic Details
Main Authors: William R. Swindell, Colin P. S. Kruse, Edward O. List, Darlene E. Berryman, John J. Kopchick
Format: Article
Language:English
Published: BMC 2019-05-01
Series:Journal of Translational Medicine
Subjects:
Amyotrophic lateral sclerosis
Biomarker
GWAS
Hypoxia
Machine learning
Microarray
Online Access:http://link.springer.com/article/10.1186/s12967-019-1909-0

Internet

http://link.springer.com/article/10.1186/s12967-019-1909-0

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