Endothelial lesion and complement activation in patients with Scleroderma Renal Crisis

Endothelial lesion and complement activation in patients with Scleroderma Renal Crisis

Abstract In kidney biopsies reviews, scleroderma renal crisis (SRC) is characterized by vascular endothelial injuries, C4d deposits on peritubular vessels, and acute and chronic injuries coexisting on the same biopsy. The clinical signs of thrombotic microangiopathy (TMA) are described in systemic s...

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Bibliographic Details
Main Authors: Ney Arencibia Pérez, María Luisa Agüera Morales, Rafael Sánchez Sánchez, Rosa María Ortega Salas, Rafael Ángel Fernández de la Puebla, Mario Espinosa Hernández
Format: Article
Language:English
Published: Sociedade Brasileira de Nefrologia 2019-02-01
Series:Brazilian Journal of Nephrology
Subjects:
Scleroderma, Localized
Thrombotic Microangiopathy
Systemic Sclerosis
Hypertensive Retinopathy
Endothelium
Complement Activation
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0101-28002019005009101&lng=en&tlng=en

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0101-28002019005009101&lng=en&tlng=en

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