ApoB-48 and apoB-100 differentially influence the expression of type-III hyperlipoproteinemia in APOE*2 mice

ApoB-48 and apoB-100 differentially influence the expression of type-III hyperlipoproteinemia in APOE*2 mice

Apolipoprotein E (apoE) is essential for the clearance of plasma chylomicron and VLDL remnants. The human APOE locus is polymorphic and 5–10% of APOE*2 homozygotes exhibit type-III hyperlipoproteinemia (THL), while the remaining homozygotes have less than normal plasma cholesterol. In contrast, mice...

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Bibliographic Details
Main Authors: Myron E. Hinsdale, Patrick M. Sullivan, Hafid Mezdour, Nobuyo Maeda
Format: Article
Language:English
Published: Elsevier 2002-09-01
Series:Journal of Lipid Research
Subjects:
lipoproteins
very low density lipoprotein
metabolism
lipoprotein remnants
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520328169

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http://www.sciencedirect.com/science/article/pii/S0022227520328169

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