The many facets of homologous recombination at telomeres

The ends of linear chromosomes are capped by nucleoprotein structures called telomeres. A dysfunctional telomere may resemble a DNA double-strand break (DSB), which is a severe form of DNA damage. The presence of one DSB is sufficient to drive cell cycle arrest and cell death. There...

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Bibliographic Details
Main Authors: Clémence Claussin, Michael Chang
Format: Article
Language:English
Published: Shared Science Publishers OG 2015-07-01
Series:Microbial Cell
Subjects:
Online Access:http://microbialcell.com/researcharticles/the-many-facets-of-homologous-recombination-at-telomeres/