Apolipoprotein E4 Alters Astrocyte Fatty Acid Metabolism and Lipid Droplet Formation
Lipid droplets (LDs) serve as energy rich reservoirs and have been associated with apolipoprotein E (<i>APOE</i>) and neurodegeneration. The E4 allele of <i>APOE</i> (E4) is the strongest genetic risk factor for the development of late onset Alzheimer’s disease (AD)...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2019-02-01
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| Series: | Cells |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2073-4409/8/2/182 |