CXCR4 expression heterogeneity in neuroblastoma cells due to ligand-independent regulation

<p>Abstract</p> <p>Background</p> <p>CXCR4, the receptor for the chemokine stromal-derived factor 1 (SDF-1), has been shown to mediate many of the processes essential for cancer progression such as tumor cell proliferation, metastasis, and angiogenesis. To understand th...

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Bibliographic Details
Main Authors: Maris John M, Carlisle Rosalind Y, Lyttle Christopher A, Carlisle Alex J
Format: Article
Language:English
Published: BMC 2009-12-01
Series:Molecular Cancer
Online Access:http://www.molecular-cancer.com/content/8/1/126