3D printed tacrolimus suppositories for the treatment of ulcerative colitis

3D printed tacrolimus suppositories for the treatment of ulcerative colitis

Ulcerative colitis is a global health problem, affecting millions of individuals worldwide. As an inflammatory condition localised in the large intestine, rectal delivery of immunosuppressive therapies such as tacrolimus is a promising strategy to maximise drug concentration at the site of action wh...

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Bibliographic Details
Main Authors: Iria Seoane-Viaño, Jun Jie Ong, Asteria Luzardo-Álvarez, Miguel González-Barcia, Abdul W. Basit, Francisco J. Otero-Espinar, Alvaro Goyanes
Format: Article
Language:English
Published: Elsevier 2021-01-01
Series:Asian Journal of Pharmaceutical Sciences
Subjects:
3D printed drug products
Semi-solid extrusion 3D printing
Inflammatory bowel disease
Suppository drug delivery
Pressure assisted syringe
M3dimaker
Online Access:http://www.sciencedirect.com/science/article/pii/S1818087620302920

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http://www.sciencedirect.com/science/article/pii/S1818087620302920

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