Which patients to sample in clinical cohort studies when the number of events is high and measurement of additional markers is constrained by limited resources

Abstract Purpose We consider an existing clinical cohort with events but limited resources for the investigation of a further potentially expensive marker. Biological material of the patients is stored in a biobank, but only a limited number of samples can be analyzed with respect to the marker. The...

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Bibliographic Details
Main Authors: Dominic Edelmann, Kristin Ohneberg, Natalia Becker, Axel Benner, Martin Schumacher
Format: Article
Language:English
Published: Wiley 2020-10-01
Series:Cancer Medicine
Subjects:
Online Access:https://doi.org/10.1002/cam4.3381