Small Molecule Inhibitors of Ceramidases

Small Molecule Inhibitors of Ceramidases

The equilibrium between the pro-apoptotic ceramide and pro-vital sphingosine-1-phosphate is considered to be decisive for cell death or survival. The different ceramidases thus play key roles in cell fate and might offer attractive targets for pharmacological intervention. Although until recently on...

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Bibliographic Details
Main Authors: Essa M. Saied, Christoph Arenz
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2014-06-01
Series:Cellular Physiology and Biochemistry
Subjects:
Ceramide
Enzyme inhibitors
Enzyme assays
Lipid probes
Ceramidases
Sphingolipids
Lipid signaling
Online Access:http://www.karger.com/Article/FullText/362995

Internet

http://www.karger.com/Article/FullText/362995

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