Low level expression of the Mitochondrial Antiviral Signaling protein (MAVS) associated with long-term nonprogression in SIV-infected rhesus macaques

Low level expression of the Mitochondrial Antiviral Signaling protein (MAVS) associated with long-term nonprogression in SIV-infected rhesus macaques

Abstract Background Abnormally increased immune activation is one of the main pathological features of acquired immunodeficiency syndrome (AIDS). This study aimed to determine whether long-term nonprogression (LTNP) suppresses the upregulation of immune activation and to elucidate the mechanisms whe...

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Bibliographic Details
Main Authors: Miaomiao Zhang, Zhuotao Fu, Jiantao Chen, Boqiang Zhu, Ye Cheng, Linchun Fu
Format: Article
Language:English
Published: BMC 2018-10-01
Series:Virology Journal
Subjects:
Simian immunodeficiency virus
Disease progression
Activation
Inflammation
LTNP
MAVS
Online Access:http://link.springer.com/article/10.1186/s12985-018-1069-5

Internet

http://link.springer.com/article/10.1186/s12985-018-1069-5

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