Low serum glutathione peroxidase activity is associated with increased cardiovascular mortality in individuals with low HDLc's.

BACKGROUND: Since oxidized LDL is thought to initiate atherosclerosis and the serum glutathione peroxidase (GPx3) reduces oxidized lipids, we investigated whether high GPx3 activity reduces cardiovascular disease (CVD) mortality. METHODS: We determined GPx3 in stored samples from the Minnesota Heart...

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Bibliographic Details
Main Authors: Brian Buijsse, Duk-Hee Lee, Lyn Steffen, Richard R Erickson, Russell V Luepker, David R Jacobs, Jordan L Holtzman
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3376150?pdf=render