Population stratification of a common APOBEC gene deletion polymorphism.

The APOBEC3 gene family plays a role in innate cellular immunity inhibiting retroviral infection, hepatitis B virus propagation, and the retrotransposition of endogenous elements. We present a detailed sequence and population genetic analysis of a 29.5-kb common human deletion polymorphism that remo...

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Bibliographic Details
Main Authors: Jeffrey M Kidd, Tera L Newman, Eray Tuzun, Rajinder Kaul, Evan E Eichler
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2007-04-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC1853121?pdf=render