Cysteine Cathepsins and Their Prognostic and Therapeutic Relevance in Leukemia

Cysteine cathepsins are lysosomal proteases that require Cys-His ion pair in their catalytic site for enzymatic activity. While their aberrant expression and oncogenic functions have been widely reported in solid tumors, recent findings suggest that these proteases also play an important role in the...

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Bibliographic Details
Main Authors: Mohit Arora, Garima Pandey, Shyam S. Chauhan
Format: Article
Language:English
Published: Thieme Medical and Scientific Publishers Pvt. Ltd. 2021-04-01
Series:Annals of the National Academy of Medical Sciences (India)
Subjects:
Online Access:http://www.thieme-connect.de/DOI/DOI?10.1055/s-0041-1726151