Polymorphisms in alcohol metabolism genes ADH1B and ALDH2, alcohol consumption and colorectal cancer.

Polymorphisms in alcohol metabolism genes ADH1B and ALDH2, alcohol consumption and colorectal cancer.

Colorectal cancer (CRC) is a leading cause of cancer death worldwide. Epidemiological risk factors for CRC included alcohol intake, which is mainly metabolized to acetaldehyde by alcohol dehydrogenase and further oxidized to acetate by aldehyde dehydrogenase; consequently, the role of genes in the a...

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Main Authors: Marta Crous-Bou, Gad Rennert, Daniel Cuadras, Ramon Salazar, David Cordero, Hedy Saltz Rennert, Flavio Lejbkowicz, Levy Kopelovich, Steven Monroe Lipkin, Stephen Bernard Gruber, Victor Moreno
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3839967?pdf=render

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http://europepmc.org/articles/PMC3839967?pdf=render

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