Mannose-binding lectin regulates host resistance and pathology during experimental infection with Trypanosoma cruzi.

Mannose-binding lectin regulates host resistance and pathology during experimental infection with Trypanosoma cruzi.

Mannose-binding lectin (MBL) is a humoral pattern-recognition molecule important for host defense. Although recent genetic studies suggest an involvement of MBL/MASP2-associated pathways in Chagas' disease, it is currently unknown whether MBL plays a role in host resistance to the intracellular...

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Bibliographic Details
Main Authors: Antonio Gigliotti Rothfuchs, Ester Roffê, Amanda Gibson, Allen W Cheever, R Alan B Ezekowitz, Kazue Takahashi, Mario Steindel, Alan Sher, André Báfica
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3490958?pdf=render

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http://europepmc.org/articles/PMC3490958?pdf=render

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