Functional Comparison of Blood-Stage Plasmodium falciparum Malaria Vaccine Candidate Antigens

Functional Comparison of Blood-Stage Plasmodium falciparum Malaria Vaccine Candidate Antigens

The malaria genome encodes over 5,000 proteins and many of these have also been proposed to be potential vaccine candidates, although few of these have been tested clinically. RH5 is one of the leading blood-stage Plasmodium falciparum malaria vaccine antigens and Phase I/II clinical trials of vacci...

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Bibliographic Details
Main Authors: Joseph J. Illingworth, Daniel G. Alanine, Rebecca Brown, Jennifer M. Marshall, Helen E. Bartlett, Sarah E. Silk, Geneviève M. Labbé, Doris Quinkert, Jee Sun Cho, Jason P. Wendler, David J. Pattinson, Lea Barfod, Alexander D. Douglas, Michael W. Shea, Katherine E. Wright, Simone C. de Cassan, Matthew K. Higgins, Simon J. Draper
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-06-01
Series:Frontiers in Immunology
Subjects:
malaria
vaccine
blood-stage malaria
antigen
merozoite
RH5
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.01254/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2019.01254/full

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