A novel and critical role for Oct4 as a regulator of the maternal-embryonic transition.

A novel and critical role for Oct4 as a regulator of the maternal-embryonic transition.

Compared to the emerging embryonic stem cell (ESC) gene network, little is known about the dynamic gene network that directs reprogramming in the early embryo. We hypothesized that Oct4, an ESC pluripotency regulator that is also highly expressed at the 1- to 2-cell stages in embryos, may be a criti...

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Bibliographic Details
Main Authors: Kira Foygel, Bokyung Choi, Sunny Jun, Denise E Leong, Alan Lee, Connie C Wong, Elizabeth Zuo, Michael Eckart, Renee A Reijo Pera, Wing H Wong, Mylene W M Yao
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2614881?pdf=render

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http://europepmc.org/articles/PMC2614881?pdf=render

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