RNA Polymerase II CTD phosphatase Rtr1 fine-tunes transcription termination.

RNA Polymerase II (RNAPII) transcription termination is regulated by the phosphorylation status of the C-terminal domain (CTD). The phosphatase Rtr1 has been shown to regulate serine 5 phosphorylation on the CTD; however, its role in the regulation of RNAPII termination has not been explored. As a c...

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Bibliographic Details
Main Authors: Jose F Victorino, Melanie J Fox, Whitney R Smith-Kinnaman, Sarah A Peck Justice, Katlyn H Burriss, Asha K Boyd, Megan A Zimmerly, Rachel R Chan, Gerald O Hunter, Yunlong Liu, Amber L Mosley
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-03-01
Series:PLoS Genetics
Online Access:https://doi.org/10.1371/journal.pgen.1008317