MicroRNA29a Reverts the Activated Hepatic Stellate Cells in the Regression of Hepatic Fibrosis through Regulation of ATPase H<sup>+</sup> Transporting V1 Subunit C1

MicroRNA29a Reverts the Activated Hepatic Stellate Cells in the Regression of Hepatic Fibrosis through Regulation of ATPase H<sup>+</sup> Transporting V1 Subunit C1

Activated hepatic stellate cells (aHSCs) play a key role in liver fibrosis. During the regression of fibrosis, aHSCs are transformed into inactivated cells (iHSCs), which are quiescent lipid-containing cells and express higher levels of lipid-related genes, such as peroxisome proliferators-activated...

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Bibliographic Details
Main Authors: Fei Jing, Yan Geng, Xin-Yi Xu, Hong-Yu Xu, Jin-Song Shi, Zheng-Hong Xu
Format: Article
Language:English
Published: MDPI AG 2019-02-01
Series:International Journal of Molecular Sciences
Subjects:
cell differentiation
fibrosis regression
hepatic fibrosis
peroxisome proliferators-activated receptors gamma (PPARγ)
vacuolar adenosine triphosphatase (V-ATPase)
Online Access:https://www.mdpi.com/1422-0067/20/4/796

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https://www.mdpi.com/1422-0067/20/4/796

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