l-arginine improves dystrophic phenotype in mdx mice

l-arginine improves dystrophic phenotype in mdx mice

A possible treatment for Duchenne muscular dystrophies would be to compensate for dystrophin loss by increasing the expression of utrophin, another cytoskeletal protein of the muscle membrane. We previously found that l-arginine, the substrate for nitric oxide synthase, significantly increased utrop...

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Bibliographic Details
Main Authors: Vincent Voisin, Catherine Sébrié, Stéfan Matecki, Hua Yu, Brigitte Gillet, Michèle Ramonatxo, Maurice Israël, Sabine De la Porte
Format: Article
Language:English
Published: Elsevier 2005-10-01
Series:Neurobiology of Disease
Subjects:
Utrophin
Dystrophin
mdx
DMD
l-arginine
Molsidomine
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996105000677

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http://www.sciencedirect.com/science/article/pii/S0969996105000677

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