Evaluation of the bioavailability of hydrocortisone when prepared as solid dispersion

This study was conducted to formulate, characterize, and investigate the bioavailability of hydrocortisone (HCT) when prepared as solid dispersions. HCT was mixed in an organic solvent with polyethylene glycol 4000 (PEG 4000) and Kolliphor® P 407. Spray drying technique was employed to form a solid...

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Bibliographic Details
Main Authors: Mohammad A. Altamimi, Ehab M. Elzayat, Wajhul Qamar, Sultan M. Alshehri, Abdelrahman Y. Sherif, Nazrul Haq, Faiyaz Shakeel
Format: Article
Language:English
Published: Elsevier 2019-07-01
Series:Saudi Pharmaceutical Journal
Online Access:http://www.sciencedirect.com/science/article/pii/S1319016419300428