Activation of the Interleukin-33/ST2 Pathway Exerts Deleterious Effects in Myxomatous Mitral Valve Disease

Activation of the Interleukin-33/ST2 Pathway Exerts Deleterious Effects in Myxomatous Mitral Valve Disease

Mitral valve disease (MVD) is a frequent cause of heart failure and death worldwide, but its etiopathogenesis is not fully understood. Interleukin (IL)-33 regulates inflammation and thrombosis in the vascular endothelium and may play a role in the atherosclerotic process, but its role in mitral valv...

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Bibliographic Details
Main Authors: Amaia Garcia-Pena, Jaime Ibarrola, Adela Navarro, Alba Sadaba, Carolina Tiraplegui, Mattie Garaikoetxea, Vanessa Arrieta, Lara Matilla, Amaya Fernández-Celis, Rafael Sadaba, Virginia Alvarez, Alicia Gainza, Eva Jover, Natalia López-Andrés
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:International Journal of Molecular Sciences
Subjects:
interleukin-33
ST2
mitral valve
myxomatous
valve endothelial cells
valve interstitial cells
Online Access:https://www.mdpi.com/1422-0067/22/5/2310

Internet

https://www.mdpi.com/1422-0067/22/5/2310

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