Mechanisms navigating the TGF-β pathway in prostate cancer

Few pharmacotherapies are currently available to treat castration resistant prostate cancer (CRPC), with low impact on patient survival. Transforming growth factor-β (TGF-β) is a multi-functional peptide with opposite roles in prostate tumorigenesis as an inhibitor in normal growth and early stage d...

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Bibliographic Details
Main Authors: Zheng Cao, Natasha Kyprianou
Format: Article
Language:English
Published: Elsevier 2015-01-01
Series:Asian Journal of Urology
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S221438821500034X