UtpA and UtpB chaperone nascent pre-ribosomal RNA and U3 snoRNA to initiate eukaryotic ribosome assembly

UtpA and UtpB chaperone nascent pre-ribosomal RNA and U3 snoRNA to initiate eukaryotic ribosome assembly

Eukaryotic ribosome biogenesis involves a large number of maturations factors which are responsible for the stepwise assembly of the ribosomal subunits. Here the authors use an array of biochemical and structural biology methods to investigate the function of the UtpA and UtpB complexes as part of t...

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Bibliographic Details
Main Authors: Mirjam Hunziker, Jonas Barandun, Elisabeth Petfalski, Dongyan Tan, Clémentine Delan-Forino, Kelly R. Molloy, Kelly H. Kim, Hywel Dunn-Davies, Yi Shi, Malik Chaker-Margot, Brian T. Chait, Thomas Walz, David Tollervey, Sebastian Klinge
Format: Article
Language:English
Published: Nature Publishing Group 2016-06-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/ncomms12090

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https://doi.org/10.1038/ncomms12090

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