The ABCC6 transporter: what lessons can be learnt from other ATP-binding cassette transporters?

ABC transporters represent a large family of ATP-driven transmembrane transporters involved in uni- or bidirectional transfer of a variety of substrates. Divided in 7 families, they represent 48 transporter proteins, several of which are associated with human disease. Among the latter is ABCC6, a un...

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Bibliographic Details
Main Authors: Olivier M. Vanakker, Mohammad Jakir Hosen, Anne eDe Paepe
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-10-01
Series:Frontiers in Genetics
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fgene.2013.00203/full