Allelic Imbalance in Regulation of ANRIL through Chromatin Interaction at 9p21 Endometriosis Risk Locus.

Genome-wide association studies (GWASs) have discovered numerous single nucleotide polymorphisms (SNPs) associated with human complex disorders. However, functional characterization of the disease-associated SNPs remains a formidable challenge. Here we explored regulatory mechanism of a SNP on chrom...

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Bibliographic Details
Main Authors: Hirofumi Nakaoka, Aishwarya Gurumurthy, Takahide Hayano, Somayeh Ahmadloo, Waleed H Omer, Kosuke Yoshihara, Akihito Yamamoto, Keisuke Kurose, Takayuki Enomoto, Shigeo Akira, Kazuyoshi Hosomichi, Ituro Inoue
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-04-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC4824487?pdf=render