Disruption of Zika Virus xrRNA1-Dependent sfRNA1 Production Results in Tissue-Specific Attenuated Viral Replication

Disruption of Zika Virus xrRNA1-Dependent sfRNA1 Production Results in Tissue-Specific Attenuated Viral Replication

The Zika virus (ZIKV), like other flaviviruses, produces several species of sub-genomic RNAs (sfRNAs) during infection, corresponding to noncoding RNA fragments of different lengths that result from the exonuclease degradation of the viral 3′ untranslated region (UTR). Over the course of infection,...

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Bibliographic Details
Main Authors: Hadrian Sparks, Brendan Monogue, Benjamin Akiyama, Jeffrey Kieft, J. David Beckham
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:Viruses
Subjects:
Zika virus
flavivirus
RNA structure
non-coding RNA
replication
antibody
Online Access:https://www.mdpi.com/1999-4915/12/10/1177

Internet

https://www.mdpi.com/1999-4915/12/10/1177

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