Irradiation‐induced polyploid giant cancer cells are involved in tumor cell repopulation via neosis

Tumor repopulation occurs when residual tumor cells surviving therapies tenaciously proliferate and re‐establish the tumor. The cellular and molecular mechanisms underlying this process remain poorly understood. In this study, we propose that polyploid giant cancer cells (PGCCs) are involved in tumo...

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Bibliographic Details
Main Authors: Zhengxiang Zhang, Xiao Feng, Zheng Deng, Jin Cheng, Yiwei Wang, Minghui Zhao, Yucui Zhao, Sijia He, Qian Huang
Format: Article
Language:English
Published: Wiley 2021-08-01
Series:Molecular Oncology
Subjects:
Online Access:https://doi.org/10.1002/1878-0261.12913