Assessment of remifentanil for rapid sequence induction and intubation in patients at risk of pulmonary aspiration of gastric contents compared to rapid-onset paralytic agents: study protocol for a non-inferiority simple blind randomized controlled trial (the REMICRUSH study)

Assessment of remifentanil for rapid sequence induction and intubation in patients at risk of pulmonary aspiration of gastric contents compared to rapid-onset paralytic agents: study protocol for a non-inferiority simple blind randomized controlled trial (the REMICRUSH study)

Abstract Background Rapid-onset paralytic agents are recommended to achieve muscle relaxation and facilitate tracheal intubation during rapid sequence induction in patients at risk of pulmonary aspiration of gastric contents. However, opioids are frequently used in this setting. The study’s objectiv...

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Bibliographic Details
Main Authors: Nicolas Grillot, Matthias Garot, Sigismond Lasocki, Olivier Huet, Pierre Bouzat, Charlène Le Moal, Mathieu Oudot, Nolwenn Chatel-Josse, Younes El Amine, Marc Danguy des Déserts, Nathalie Bruneau, Raphael Cinotti, Jean-Stéphane David, Olivier Langeron, Vincent Minville, Martine Tching-Sin, Elodie Faurel-Paul, Céline Lerebourg, Delphine Flattres-Duchaussoy, Alexandra Jobert, Karim Asehnoune, Fanny Feuillet, Antoine Roquilly
Format: Article
Language:English
Published: BMC 2021-03-01
Series:Trials
Subjects:
Rapid sequence induction
Full stomach patient
Remifentanil
Paralytic agents
Succinylcholine
Rocuronium
Online Access:https://doi.org/10.1186/s13063-021-05192-x

Internet

https://doi.org/10.1186/s13063-021-05192-x

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